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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c05bc5fbe1f04b9467eaccfd52c5d15e7e7167469067788a1ce8fb24f0c7b10' 
  AND token = 'bX9VvruyaikZ9OxM5aAsuQAQ2AWNpmJlR2LZ2cFkf/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}