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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f00721f71ecf60c0f0d8d20812681085ccbd2e833d2dedf4703d261acd4af2' 
  AND token = 'o4XUmqf+SxtahuAn7cui1A6n1w39paKpZx9QT7XE/ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}