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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740c6666edca88a5acbcc6ad3ff406867449da6d1a14f3dc651545d681378a82' 
  AND token = 'tHNfMUji7nSEXnBtHQZVGVamGCKX9/+fjqpSANr41DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}