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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e6665cb31b2306fa65adfca28118e46e484f9defb4a49d219bbaf2dcf97a3e' 
  AND token = 'Na/IFwxWdjphU9oPhlGuexrV99YXsO8yg6IMCNsEA7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}