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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b28a9104492aeaf471b50f5c4bd083d790e2316c8c94163ca7445cc3bc9b7666' 
  AND token = 'EErU9RcnKmHbWHe7rrAUISa8x2qdznUxvahbm3F2oC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}