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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b52e06b5b9b48164c04d6e4233287308ff1782995fb9af1d942551f6518a3a6' 
  AND token = 'mALZSd7Je3bC73pS9Md8MMizXswdLhyIogwtRZ4SVSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}