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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a704e853e20b32f485f8f3df32be4ec5ba0cd5ccfcd462a0aa1091919da14b' 
  AND token = 'TlHUl8Hd6ijcuJ+rXa/uA3Pq19A+IW70vnsQj11Nf1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}