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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53f1f4548c3f72c7245d33f0cfddde084034c50702dc000b034f5786836c9f0' 
  AND token = 'ynVpSPjtKUAapKcX8e5kXiX1M34RRP9+tx9au4ypBC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}