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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5054149f2d4688589e8da4335b3c4782c7d86e9c78d6ffd85b9ef2989980aef2' 
  AND token = 'PQDh7ngw4IVt+3d+3bHav8AstwnqPydOK5xR2D2l4YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}