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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77fd5400b3fd54ee0a8897d2f396d52bfd1e9b7e0f1a00b5f612694668af91fe' 
  AND token = 'sb7uutmOD0P72UAzi2gmuAoFKZ2J0bnL2riCzmwbeL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}