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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2498ed712dd471f70dd6e16d74c1549065072da2a339273e4bac35134af39d1c' 
  AND token = 'vtwVZW1lyMylF1VfioeZAxwRc4QNm28VDo81BBAA8H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}