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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41e57ea30129f598819b884c9b5aed210d67dd60ac2d987c7f5e59c257a454c' 
  AND token = '75EFtw/XxFmHWUgITkTnEhYvXFdYQPOgfTqRSW1OQSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}