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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0c153f9b6b4d58dba7b7fe25e3dc29dbbda2194b93fa45bb25a09450642612' 
  AND token = '3y6iVtkWBd+1j5LAiJKD86UX5aKMMKsqKu4qBxEG1Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}