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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c602a071557ec81380c3f9af44c6b8bff66f66e44a8bd6af1b78f7af01e134' 
  AND token = 'wTizmS5YiKGw2z3efzQzd/5610l7SnNTMnwFxcrOowo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}