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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21626539df9c302fa45c59bc0ba3b624084afdf04d914f9e68e2e265a2b4aa59' 
  AND token = '814qagzHZ/KEOv4tT2RoYFsP59k4TPBijboReNNE1C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}