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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6211dc8796ba3cc0251ff6f7d89f1c8ba2353fdf9e6652e9ff42ccb9e402c9a5' 
  AND token = 'wDvPLpgvGdi26Y2QcN+4iWn+2EvhbG2lkHyZTwiUv0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}