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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7351ff7a5efb37d78b70fed9adc257a29740257e42fde4ef44d2bbf345b12f1c' 
  AND token = '8Jjq0I3pcn4eKVGPRBjkGe8cfgfLdYQ9tyLudUJWqCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}