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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c42baf2e1a86fc137faf56bf50ef640a5ec48f457f4a7363f2a59dacf144c50' 
  AND token = 'I0d5AEWzzH+owzyz1DmZvtdUXrTND6oZLVew7B4n9wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}