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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7129bf6a9a20c92487ff2511f08f9c14e93e65383c8e39adeb7c0c2a673d427f' 
  AND token = 'P8hiDJcPf0bql+HUQ0kw83UFQhb5JudMJs83Cd1qnrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}