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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db4c485098adabd3c1a2232b4e8a3d814787f22d4fd18a06fe252683bf90e143' 
  AND token = 'yJBbGrtJ/eUj6x7449GCli7p9dI7nVS7RsgMp0FTIj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}