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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '600b79d9f986cc7e76cd5da8e3724b41a2121ebb58afd5e52fab36154e1a1d5b' 
  AND token = '1eMoEpgEZelU0UHjw9dn9gDAfBTednzvoFhprRfg+SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}