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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '820eb64b3f049159f7078738a6174c1b428b98feeb1505e15650342069d30f16' 
  AND token = 'U6QYxTxD/GT1dd6YA3TbFyD9Kq9DkzDkJvoCLPwOwA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}