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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53c60c4d27c4872334c7e5d88704fdc5b9198d0c1e0398e18d31c940b3a7243' 
  AND token = '3+hL6tNuXz6NCjcBjEYkIODGZ/frN9zvhqLiSd5khrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}