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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0de1af6654250648949974ed316f4f6af6bc5f723625e62a8d8cdb20e38d195' 
  AND token = 'XfCLM6k3dUT9S9tgdDmilzMZdCC/H5R6+U5v1oLmJxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}