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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9387be965ffc78aabcab11cf86e2ed182bb1a6db005024dc4f6b2972edeeba5' 
  AND token = 'eQpEtt6nvsoXfaMIx3MxPa93cEI1AWN6g7peEL/JZe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}