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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33bd1d36f73fd2340a2ed48e165086537206d873fbeb822e7a6a6d1c1c1699b4' 
  AND token = 'SuUXy4QH7TiSfwIYhptY7RcURG9rkNgv2vYdzGFnh3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}