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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ffddc3d541748e5c7b9e36127727760bb4dc5cd0419d748e5deaaec41849e35' 
  AND token = 'nRegIhow7+Svlt3AnJNBGiCOWKoDDtBbbCOG95KaI4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}