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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb50a4f66acb06647405695985ba1de2ba1ec67feaf39afe9a3c80db87aab7f' 
  AND token = 't1hZ5O6Lv2GctqpukVItV0xtugCW81HxGpitS5JNHfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}