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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377b765e43a513e43343b33477a342900794a8c5e5d3597700670da04cd912d4' 
  AND token = '6UaDDK+BWoM7/WllKj3mbphJPFNpJOwDEvuk+z2N2xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}