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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c5303e5190e1d80787fc33ed2ddfd07ff285b574184b1a3ae618e35b81739d0' 
  AND token = 'igtdRI2LfTrZx7pUKCeSow7aJ+suFh6H9N0Y2QBGscI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}