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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7978ab9b14e7e62b696a73eff2e37a3012fbad6dad95af7bfa4d532d53d0d2b' 
  AND token = 'Bg20+qZF0MEodcFwq7LeIVSvNQ27/W/JnLlcqpYu/tY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}