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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e5cc59d3c0f20194aa9edefb233aa778058265cadf48159ed19ba09044e677' 
  AND token = 'wgWO3aphr5rKNs0LqlBdi8BXZD2MS3aHsaGFIctzTW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}