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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '274adb1d8d02f10cb7eddc687c0914e0ae11a7b6a3d90f87522e5c389eb36df2' 
  AND token = 'KpU0c0V8yKpUoXooZsveIyeRuZ0YMiuwBh/Mf5ionBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}