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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422136d13a85185d119087edef94fa8ce0b597d62765900ab34f4d85657cd55a' 
  AND token = 'ey2QUEiFjQDsRU0dj+mTqbWQ72DixgBSzEzg5KFkdzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}