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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '188becc621d3a435e3df0047abd81c127be9eebd038a87df1159405dcdd0452d' 
  AND token = 'HZ9pOgGLCy3sBkC1/iw1xuV0u9xO8JqWAsjOtY2Zl9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}