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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424eeae7339ad8d3cef2aaae279c4193f76da0952371c1528bf119bed26af229' 
  AND token = 'Ill41OwdmZGyujDIftgrXdsVCtaF4smEe++es/37UJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}