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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f965ef13464eb1f659bff9d89833f1e2dab3dcdf7258a50e2c911b0bf2954d5' 
  AND token = 'jtE5XnPO+q4v29KMZJItbPDkzPby3aY2riyrMY7wj1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}