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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '519df242fe89f1120cce5dc73788d2012aed6a773133be8c5061e596521f87a6' 
  AND token = 'KAFXhOYMY/u5LffHhB9eh9ZSWtIWzXJWw4yytXEe3GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00094

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}