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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41438400c81c9c842a04aaff52979214c7efcf5c805e8de5810a79ed771089fd' 
  AND token = 'ETGdr8Cwo2V23IN0S0N4NucqFicHszy45ZR6Fh0oSy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}