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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dedd52fedd93f2e7cf602c5af64b0cc41b055c2407a7f95d0252f3626f3593b1' 
  AND token = 'a/K/6hvC5wfMaFnvXQowe3MiGsR8aUGZ451VIB6OXuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}