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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a807a01f5ed0be40269bd56dcbe1f21fd9c305f04271d348c7b0d947edbbf8b' 
  AND token = 'DbPau21Ps1WZeKDx73jOX1bGUNbxiPNf1t4eN+6W+ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}