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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51d695e6a636c6a1513ac6dd3e58e17d18480203c71ee152927f005f6816369b' 
  AND token = 'b78tyr0cnm8tXQzHQ4SPcbQc+JMtcH4+Zo/3qys4hGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}