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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5125c15b0cf1ad0bc33bce39725b19f4b9bd0b40650f8a485cafe5a69cc996b3' 
  AND token = '04SVgOFzQBj45pjR0uAY09mQ06U3JT+2Vnb7duIDkms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}