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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e1d8d2e28678dcc1f589365b3e85305fbad20974da53d453206f2041469a0ea' 
  AND token = 'mYu2nR4JHfPK2UV6DlGZwV+wkSo69870F4xW5iMahaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}