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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45eb12bee2f73e54317130062de41ea28677b7d491689ea4e4e87bd3d049b50b' 
  AND token = 'x1V20YGkWlYmmwsawRa4qz/R/xAFZFcdSCEJIiujea0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}