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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bbc729ad563b46a9f29341f9d51fd78bd3f349b07f3a6b61312f827b9d708a8' 
  AND token = 'LHEqfpWLmPtxBfHdMIqnVbI8y+W4nGD81lDPBTY72OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}