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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef2c42162e5207e5ace2e33c583dd8721b4c5ff38844eaf8ccf41a2c51a6f2a' 
  AND token = '49HHOfRVdEk8eEsf6A46Cw2SBT4FNe6bJhar9/nRDt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}