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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af24d979d7054813eabc3a03bc3d6afe7e85fa31669e817c8f155bcd5b66d7b5' 
  AND token = 'iThLSICmsGwgbobw36IQGbAn1HCZlg2AMBvlSqMoNNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}