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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '815d6e06318dd14427be5b4fde894fc2c7d7b54a2d9d35fb12bc1040224acb29' 
  AND token = 'o6Mm+aqQV6c1Xky0Vq2XDusc+L4gnVPnQ6sEhkh9kpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}