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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e8c176e0d84607f1230058c91b0c3b77e35f3a08fe024a69203e1ec4e8a1b5' 
  AND token = 'c3qPlPXXdRz07zB8bitgFGPmt42eQLOdJfGyQPcgfSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}